{"id":318549,"date":"2023-11-29T09:11:16","date_gmt":"2023-11-29T08:11:16","guid":{"rendered":"https:\/\/polishscience.pl\/?p=318549"},"modified":"2023-11-29T09:11:16","modified_gmt":"2023-11-29T08:11:16","slug":"researchers-from-the-university-of-gdansk-demonstrated-the-effectiveness-of-genistein-in-huntingtons-disease","status":"publish","type":"post","link":"https:\/\/www.polishscience.pl\/en\/researchers-from-the-university-of-gdansk-demonstrated-the-effectiveness-of-genistein-in-huntingtons-disease\/","title":{"rendered":"Researchers from the University of Gdansk demonstrated the effectiveness of genistein in Huntington&#8217;s disease"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Researchers at the University of Gdansk have demonstrated on an animal model the effectiveness of genistein in Huntington&#8217;s disease. The findings were published in the journal Autophagy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Genistein is a chemical compound from the flavonoid group that is found in broad bean plants. Treatment with genistein stimulates the autophagy process in the brains of mice, leading to a correction of Huntington&#8217;s disease symptoms, suggesting that the compound could be considered as a potential drug. Huntington&#8217;s disease is a genetic disorder that causes progressive degeneration of brain cells, leading to motor and cognitive impairment.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Combined with a report indicating that impaired autophagy may be a major cause of neurodegenerative changes, these findings suggest a route to developing effective therapeutic approaches for various neurodegenerative diseases by testing compounds (or possibly combinations of compounds) capable of stimulating autophagy and\/or unblocking this process.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Read more: <\/span><a href=\"https:\/\/ug.edu.pl\/news\/pl\/6112\/publikacja-zespolu-prof-grzegorza-wegrzyna-w-prestizowym-czasopismie\"><span style=\"font-weight: 400;\">https:\/\/ug.edu.pl\/news\/pl\/6112\/publikacja-zespolu-prof-grzegorza-wegrzyna-w-prestizowym-czasopismie<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the University of Gdansk have demonstrated on an animal model the effectiveness of genistein in Huntington&#8217;s disease. The findings were published in the journal Autophagy. Genistein is a chemical compound from the flavonoid group that is found in broad bean plants. Treatment with genistein stimulates the autophagy process in the brains of mice, [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":318515,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[27],"tags":[],"_links":{"self":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/318549"}],"collection":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/comments?post=318549"}],"version-history":[{"count":1,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/318549\/revisions"}],"predecessor-version":[{"id":318557,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/318549\/revisions\/318557"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/media\/318515"}],"wp:attachment":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/media?parent=318549"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/categories?post=318549"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/tags?post=318549"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}