{"id":263047,"date":"2023-01-26T12:58:49","date_gmt":"2023-01-26T11:58:49","guid":{"rendered":"https:\/\/polishscience.pl\/?p=263047"},"modified":"2023-01-26T13:00:05","modified_gmt":"2023-01-26T12:00:05","slug":"jagiellonian-university-research-team-makes-breakthrough-discovery-on-albicidin-action","status":"publish","type":"post","link":"https:\/\/www.polishscience.pl\/en\/jagiellonian-university-research-team-makes-breakthrough-discovery-on-albicidin-action\/","title":{"rendered":"Jagiellonian University research team makes breakthrough discovery on albicidin action"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Professor Jonathan Heddle&#8217;s research team at the Jagiellonian University (UJ)&#8217;s Ma\u0142opolska Biotechnology Centre in Krakow has made a breakthrough discovery regarding the action of albicidin, an antibiotic that is considered the most effective substance against antibiotic-resistant bacteria.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Albicidin is known to be highly effective against E. coli and S. aureus bacteria. (Staphylococcus aureus). These bacteria are known to become increasingly resistant to currently used antibiotics, translating into an urgent need to find new, more effective drugs.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The new antibiotic targets an enzyme found in both plants and bacteria, called gyrase. Under normal circumstances, gyrase immediately fuses the torn parts of the bacteria&#8217;s DNA, but albicidin prevents this fusion, resulting in DNA disruption and bacterial death.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Prof Jonathan Heddle&#8217;s research team from the UJ made the breakthrough discovery in collaboration with the laboratories of Prof Roderich S\u00fcssmuth from the Technical University of Berlin and Dr Dmitry Ghilarov from the John Innes Centre in the UK.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Read more:\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41929-022-00904-1\"><span style=\"font-weight: 400;\">https:\/\/www.nature.com\/articles\/s41929-022-00904-1<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Professor Jonathan Heddle&#8217;s research team at the Jagiellonian University (UJ)&#8217;s Ma\u0142opolska Biotechnology Centre in Krakow has made a breakthrough discovery regarding the action of albicidin, an antibiotic that is considered the most effective substance against antibiotic-resistant bacteria. Albicidin is known to be highly effective against E. coli and S. aureus bacteria. (Staphylococcus aureus). These bacteria [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":262963,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[27],"tags":[],"_links":{"self":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/263047"}],"collection":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/comments?post=263047"}],"version-history":[{"count":1,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/263047\/revisions"}],"predecessor-version":[{"id":263055,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/263047\/revisions\/263055"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/media\/262963"}],"wp:attachment":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/media?parent=263047"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/categories?post=263047"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/tags?post=263047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}