{"id":193044,"date":"2021-09-03T15:38:48","date_gmt":"2021-09-03T13:38:48","guid":{"rendered":"https:\/\/polishscience.pl\/?p=193044"},"modified":"2021-09-03T15:38:48","modified_gmt":"2021-09-03T13:38:48","slug":"scientists-from-the-university-of-warsaw-developed-a-new-method-of-selecting-compounds-that-fight-sars-cov-2","status":"publish","type":"post","link":"https:\/\/www.polishscience.pl\/en\/scientists-from-the-university-of-warsaw-developed-a-new-method-of-selecting-compounds-that-fight-sars-cov-2\/","title":{"rendered":"Scientists from the University of Warsaw developed a new method of selecting compounds that fight SARS-Cov-2"},"content":{"rendered":"<p><strong>Researchers from the University of Warsaw (UW) under the supervision of Prof.\u00a0Jacek Jemielity from CeNT UW and Dr\u00a0Joanna Kowalska from the Faculty of Physics, University of Warsaw, have developed a new method of selecting compounds that counteract the formation of SARS-CoV-2 viral proteins.\u00a0The results of the research may be used in the treatment of COVID-19.<\/strong><\/p>\n<p>Researchers from the University of Warsaw searched for substances that would be able to effectively disrupt the expression of the genetic material of the SARS-CoV-2 virus. They analyzed the possibility of using inhibitors of nsp14 methyltransferase- the enzyme of the SARS-CoV-2 virus. The activity of this enzyme causes the multiplication of the SARS-CoV-2 virus.<\/p>\n<p>Researchers developed a fluorescence-based high-throughput screening method to select compounds capable of inhibiting viral methyltransferase.\u00a0The developed method allowed to select 83 out of 7,000 compounds that may inhibit the activity of the viral enzyme.<\/p>\n<p>The research results were published in the scientific journal &#8220;Antiviral Research&#8221;:<br \/>\n<a href=\"https:\/\/translate.google.com\/translate?hl=ru&amp;prev=_t&amp;sl=pl&amp;tl=en&amp;u=https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0166354221001327\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0166354221001327<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from the University of Warsaw (UW) under the supervision of Prof.\u00a0Jacek Jemielity from CeNT UW and Dr\u00a0Joanna Kowalska from the Faculty of Physics, University of Warsaw, have developed a new method of selecting compounds that counteract the formation of SARS-CoV-2 viral proteins.\u00a0The results of the research may be used in the treatment of COVID-19. [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[27],"tags":[],"_links":{"self":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/193044"}],"collection":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/comments?post=193044"}],"version-history":[{"count":0,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/193044\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/media?parent=193044"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/categories?post=193044"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/tags?post=193044"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}