{"id":190585,"date":"2021-08-13T15:04:41","date_gmt":"2021-08-13T13:04:41","guid":{"rendered":"https:\/\/polishscience.pl\/?p=190585"},"modified":"2021-08-13T15:04:41","modified_gmt":"2021-08-13T13:04:41","slug":"wroclaw-university-of-science-and-technology-working-on-a-prodrug-that-destroys-breast-cancer-cells","status":"publish","type":"post","link":"https:\/\/www.polishscience.pl\/en\/wroclaw-university-of-science-and-technology-working-on-a-prodrug-that-destroys-breast-cancer-cells\/","title":{"rendered":"Wroc\u0142aw University of Science and Technology working on a prodrug that destroys breast cancer cells"},"content":{"rendered":"<p><strong>The team of Prof.\u00a0Marcin Por\u0119ba from the chemical department of the Wroc\u0142aw University of Science and Technology is developing a new method of cancer biomarker analysis, and a new prodrug, i.e. a molecule that will attack and destroy cancer cells.\u00a0The scientists received a grant from the National Science Center for their research.<\/strong><\/p>\n<p>First, scientists will create chemical markers equipped with metals for specific enzymes: proteases and protein kinases &#8211; two main groups of enzymes that, depending on the situation (biological context), play a pro-tumor or anti-tumor role in the cell.\u00a0Later, they will use them in various biological systems to influence cancer cells taken from patients with breast cancer.<\/p>\n<p>The final stage of the work will be the development of antibody-drug conjugates that will activate only with selected enzymes.\u00a0In this way, scientists will create solution delivering and activating the drug in cancer cells.<\/p>\n<p>More:\u00a0<a href=\"https:\/\/translate.google.com\/translate?hl=ru&amp;prev=_t&amp;sl=pl&amp;tl=en&amp;u=https:\/\/pwr.edu.pl\/uczelnia\/aktualnosci\/na-pwr-trwaja-prace-nad-prolekiem-niszczacym-komorki-nowotworow-piersi-12121.html\">https:\/\/pwr.edu.pl\/uczelnia\/aktualnosci\/na-pwr-trwaja-prace-nad-prolekiem-niszczacym-komorki-nowotworow-piersi-12121.html<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The team of Prof.\u00a0Marcin Por\u0119ba from the chemical department of the Wroc\u0142aw University of Science and Technology is developing a new method of cancer biomarker analysis, and a new prodrug, i.e. a molecule that will attack and destroy cancer cells.\u00a0The scientists received a grant from the National Science Center for their research. First, scientists will [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[27],"tags":[],"_links":{"self":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/190585"}],"collection":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/comments?post=190585"}],"version-history":[{"count":0,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/190585\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/media?parent=190585"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/categories?post=190585"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/tags?post=190585"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}