{"id":175811,"date":"2021-04-21T13:32:54","date_gmt":"2021-04-21T11:32:54","guid":{"rendered":"https:\/\/polishscience.pl\/?p=175811"},"modified":"2021-04-21T13:32:54","modified_gmt":"2021-04-21T11:32:54","slug":"researchers-of-the-university-of-silesia-received-patent-for-a-styrylquinazolinone-derivative","status":"publish","type":"post","link":"https:\/\/www.polishscience.pl\/en\/researchers-of-the-university-of-silesia-received-patent-for-a-styrylquinazolinone-derivative\/","title":{"rendered":"Researchers of the University of Silesia received patent for a styrylquinazolinone derivative"},"content":{"rendered":"<p><strong>Chemists from the Faculty of Science and Technology at the University of Silesia have developed a substance showing several times better effectiveness in the treatment of colon cancer than imatinib, which was used so far.\u00a0The authors of the patented invention are Dr Eng.\u00a0Jacek Mularski, Dr Katarzyna Malarz and Prof.\u00a0Robert Musio\u0142.<\/strong><\/p>\n<p>The developed styrylquinazolinone derivative may be particularly useful in oncological patients with damage to the p53 protein.\u00a0This protein is called the genome guardian.\u00a0It is responsible, for activating the repair mechanisms of DNA damaged by disease.<\/p>\n<p>Treatment of patients with diagnosed cancers who develop such damage is much more difficult and is often associated with a worse prognosis.\u00a0That is why it is so important to search for new chemical compounds that can positively affect the course of therapy.\u00a0The new styrylquinazolinone derivative brings such new hopes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chemists from the Faculty of Science and Technology at the University of Silesia have developed a substance showing several times better effectiveness in the treatment of colon cancer than imatinib, which was used so far.\u00a0The authors of the patented invention are Dr Eng.\u00a0Jacek Mularski, Dr Katarzyna Malarz and Prof.\u00a0Robert Musio\u0142. The developed styrylquinazolinone derivative may [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[28,27],"tags":[],"_links":{"self":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/175811"}],"collection":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/comments?post=175811"}],"version-history":[{"count":0,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/175811\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/media?parent=175811"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/categories?post=175811"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/tags?post=175811"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}