{"id":151311,"date":"2020-10-26T14:24:33","date_gmt":"2020-10-26T13:24:33","guid":{"rendered":"https:\/\/polishscience.pl\/?p=151311"},"modified":"2020-10-27T21:26:18","modified_gmt":"2020-10-27T20:26:18","slug":"prof-marcin-drag-deciphered-another-coronavirus-protease","status":"publish","type":"post","link":"https:\/\/www.polishscience.pl\/en\/prof-marcin-drag-deciphered-another-coronavirus-protease\/","title":{"rendered":"Prof. Marcin Dr\u0105g deciphered another coronavirus protease"},"content":{"rendered":"<p><strong>Prof. Marcin Dr\u0105g of the Wroc\u0142aw University of Science and Technology, together with scientists from Poland, Germany and Belgium, managed to identify chemical compounds that neutralize the SARS-CoV-2 virus in infected human cells. The study results were published in &#8220;Nature Chemical Biology&#8221;.<\/strong><\/p>\n<p>Scientists identified and successfully tested molecules that strongly inhibit SARS-CoV-2 replication. &#8211; It&#8217;s the beginning. I hope that it can be clinically tested soon &#8211; says Prof. Dr\u0105g.<\/p>\n<p>The identified compound is an inhibitor, i.e. a substance capable of inhibiting the activity of the Mpro protease &#8211; an enzyme created in the human cell by the coronavirus. When a virus enters a human cell, it causes it to produce a complex of viral proteins. From this protein complex, two proteases are released, which further &#8220;cut&#8221; it into pieces. In this way, more proteins are created that enable the virus to multiply.<\/p>\n<p>More: <a href=\"https:\/\/pwr.edu.pl\/uczelnia\/aktualnosci\/kolejna-proteaza-z-koronawirusa-rozszyfrowana-przez-grupe-prof-marcina-draga-11757.html\">https:\/\/pwr.edu.pl\/uczelnia\/aktualnosci\/kolejna-proteaza-z-koronawirusa-rozszyfrowana-przez-grupe-prof-marcina-draga-11757.html<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prof. Marcin Dr\u0105g of the Wroc\u0142aw University of Science and Technology, together with scientists from Poland, Germany and Belgium, managed to identify chemical compounds that neutralize the SARS-CoV-2 virus in infected human cells. The study results were published in &#8220;Nature Chemical Biology&#8221;. Scientists identified and successfully tested molecules that strongly inhibit SARS-CoV-2 replication. &#8211; It&#8217;s [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[27],"tags":[],"_links":{"self":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/151311"}],"collection":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/comments?post=151311"}],"version-history":[{"count":0,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/posts\/151311\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/media?parent=151311"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/categories?post=151311"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.polishscience.pl\/en\/wp-json\/wp\/v2\/tags?post=151311"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}